Is coeliac disease hereditary? Everything you need to know
If you're wondering if Coeliac disease is hereditary., You should know that the disease itself is not, but the genes that cause it are. Given that genetic predisposition is one of the necessary factors for the development of the disease. For this reason, if you are coeliac and are expecting a child, there is a probability that they will be a Coeliac baby What gene carries the disease-causing mutation.
If you want to know more about the Coeliac disease, the Coeliac disease in babies or about Coeliac pregnancy, we invite you to read the following sections. Let's begin!
Coeliac disease and pregnancy: Is your child likely to be coeliac?
If a person diagnosed with coeliac disease is expecting one or more babies, There is a probability that their successor may also have this disease during their lifetime. However, coeliac disease is not an illness that is strictly genetic or congenital. This means that it will not manifest from the baby's birth.
One thing that needs to be made clear is that coeliac disease itself is not transmitted from parents to children, but rather the genetic risk of developing it can be. So, what the baby inherits are the genes, Coeliac disease HLA, can cause coeliac disease at any point in their life. This is not just a coeliac gene, but rather the genes known as HLA DQ2 and HLA DQ8. According to Sanitas, 95% of patients with coeliac disease have the first genetic variation mentioned, whilst the remaining 5% have the second genetic variation.
So, when faced with a genetic test, it's possible that someone with coeliac disease might have a test for HLA-DQ2 positive and DQ8 negative. Faced with this situation, it is very important to place the adult or child patient under medical supervision to begin appropriate treatment to improve their quality of life and take care of their health.
Coeliac disease is caused by an abnormal immune response to gluten, a protein found in wheat, barley, and rye.
Now we know that to say that Coeliac disease is hereditary it's not entirely correct and we can differentiate the genetic causes of this disease. Furthermore, we are clear that the Coeliac disease in babies not necessarily from childhood, but can develop after a few years.
Define one Cause of coeliac disease It's complicated, as the cause of this illness isn't entirely clear and it's also known that there isn't just one. Some of the causes that lead to coeliac disease are the mix of certain genes with gluten consumption, intestinal infections, poor childhood diet, and gut bacteria.
The reaction of a coeliac person's body to consuming gluten is different from that of a person who does not suffer from this condition. The immune system reacts negatively to gluten intake and damages the villi that line the small intestine. With these damaged villi, the intestine cannot absorb minerals, vitamins, and other nutrients from food. In other words, the body does not receive proper nourishment due to the damaged villi and does not gain the nutritional benefit of food. This can lead to malnutrition, bone weakness, lactose intolerance, cancer, nervous system problems, and infertility and/or miscarriages.
In addition to the causes we mentioned previously, there are some groups of people who have an extra risk factor for suffering from coeliac disease. Clear examples include people with Down's syndrome, Turner's syndrome, those who have family members with coeliac disease or dermatitis herpetiformis, those who suffer from hepatitis 1, autoimmune thyroid disease, and Addison's disease.
Genetic testing for coeliac disease: how reliable is it?
While stating that Coeliac disease is hereditary It is not correct; it is possible to determine through a genetic test if a child or a first-degree relative has genes that can develop coeliac disease.
These genetic tests are carried out with the aim of finding the gene HLA coeliac disease and is carried out via a saliva sample or a blood test. If the result is negative, coeliac disease is ruled out. Conversely, if the genetic test yields a positive result, it does not mean that by having the Celiac gene not necessarily means that person will develop coeliac disease at some point. It simply means that the person has a higher genetic predisposition for coeliac disease, but it is not a definitive diagnosis.
Having this genetic predisposition but not having developed coeliac disease, specialists recommend repeating the test every couple of years and having regular health checks to rule out the disease and maintain good health.
Conclusion
During the text, you learned that more than Coeliac disease is hereditary The transmission of the HLA gene can make a person genetically more prone to coeliac disease. For this reason, if you have coeliac disease and are unsure whether a first-degree relative or your daughter suffers from this condition, you can carry out a genetic test to check if they have this Celiac gene Oh no.
On the other hand, remember that coeliac disease can occur not only due to genetic inheritance, but there are other risk factors to consider when thinking about whether it's possible to have this illness or not. If you have any doubts or health problems, consult a doctor to undergo the relevant tests and thus obtain an accurate diagnosis of your health status.
Article written by the El Miracle team